A put somebody through the mill in the order of chemotherapy?
I heard scientists are trying to make chemo much more effective by single attacking the cancerous cells instead of the whole body. If this is true and if/when chemo gets to this point could everyone enjoy chemotherapy all the time running though our blood because then if we do develop cancer it will be 'attacked' immediately increasing our chance of survival.
s chemotherapy specific to different cancers, im not sure or is it a general substance that is used for adjectives cancers?
Although even if it is specific couldnt everyone have all the different types running through our body if scientists found a approach so they only attack cancer cells.
I know this is a big if, but if there is a kismet we can find a way to make it so chemo only attacks the cancer cell isnt this what we should be focusing on?
Answers:
Chemo have a lot of negative side effects so there is no providence that I would be willing to experience these things constantly.
ea and vomiting
Diarrhea or constipation
Anemia
Malnutrition
ry loss
Depression of the immune system, hence (potentially lethal) infections and sepsis
Psychosocial distress
Weight loss or gain
ndary neoplasms
Cardiotoxicity
Hepatotoxicity
Nephrotoxicity
ble is - all cancers are different - the other problem is - everyone has cancer contained by them - what it does not have is the trigger to set it off.
That is where the problems tale - the advances made in cancer treatment are astounding and progressing so fast presently - one day it may be possible to treat all cancers surrounded by one hit - who knows for sure.
mpossible, Source(s): nurse
If you had chemo drugs in your body every light of day, your blood count could go down so low that you will die.
If you want a chemo drug to kill only the cancer cell, than you would have to change the way your cell gow...impossible.
Julie, every cell has that protein. It's normally still in healthy, normal cell. NF-kappa-B is a protein found in both normal and tumor cells. It is typically immobile because it is bound by another protein called inhibitor of kappa B (I-kappa B)-alpha. When this inhibitor protein is broken down by proteasomes, the NF-kappa-B is now active and can travel to the nucleus where on earth DNA lives. Once there, the active NF-kappa-B starts a chain of events that promote tumor growth and spread.
My first sentence be directed at Jamand and the assertion that everyone has cancer cells in them.
e is a certain protein that cancer cell carry that no other cells in our body fetch. They are trying to create something to target that protein.
Trust me, it does work. I was given less than a month to live with 0% within 2000.
What they did it take T-cells that were collected from me before I ever have any chemo put in my body. They created a vaccine and used it along with interleuken 2. It was designed to attack and waste that protein which the cancer cells carry.
I was the first soul to try this and it did work. It was at the National Cancer Institute in Bethesda, MD, which is where most of the drugs are created.
Although these spanking new medications are more targeted they still have serious side effects and have the potential to injure healthy cells. Old chemotherapeutics attacked any rapidly dividing cell. This leads to side effects like reducing the immune system, anemia, nausea, diarrhea, hair loss, mouth sores, etc. The bin liner of the GI tract, blood cells, hair follicles are all fast dividing cells.
e new medications try to target features that are predominantly found surrounded by in cancer cells. Over expression of certain receptors, the obligation to stimulate new blood vessel growth are some examples. These features though can be found in healthy cell. Certain treatments for lung and colon cancer can cause painful skin rashes since skin cell contain the same receptors the medication. Blocking the growth of new blood vessels can increase the risk of both bleeding and clotting.
Further more treatments are specific for trustworthy cancers. Even within the same cancer, some targeted therapy are worthless if specific mutations are present in the cancer cells.
Secondly, both chemo and radiotherapy work on cancer because they are whats known as cytotoxic - toxic to cells. As well as slaughter cancer cells - this toxicity also makes them carcinogenic in themselves - which is why neither treatment is used for any other complaint except cancer - where the risk/benefit ratio is the right way around. Thus to give chemo to someone lacking cancer - you would be more likely to cause a cancer than 'cure' or prevent one in such untimely stages that you seem to be talking about.
Finally cancer cell rarely start 'in the blood' unless you have leukaemia (and even that starts within the bone marrow where blood cells are made) - chemo agents are administered intravenously as that's the best way to receive the drugs to the site they are needed (and unfortunately also to places they are not - hence all the side effects mentioned in a previous answer). With this contained by mind, I can't see how you can get a cell killing drug in to any factor of the body that won't at least affect the blood cells that have to convey the drug around.
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s chemotherapy specific to different cancers, im not sure or is it a general substance that is used for adjectives cancers?
Although even if it is specific couldnt everyone have all the different types running through our body if scientists found a approach so they only attack cancer cells.
I know this is a big if, but if there is a kismet we can find a way to make it so chemo only attacks the cancer cell isnt this what we should be focusing on?
Answers:
Chemo have a lot of negative side effects so there is no providence that I would be willing to experience these things constantly.
ea and vomiting
Diarrhea or constipation
Anemia
Malnutrition
ry loss
Depression of the immune system, hence (potentially lethal) infections and sepsis
Psychosocial distress
Weight loss or gain
ndary neoplasms
Cardiotoxicity
Hepatotoxicity
Nephrotoxicity
ble is - all cancers are different - the other problem is - everyone has cancer contained by them - what it does not have is the trigger to set it off.
That is where the problems tale - the advances made in cancer treatment are astounding and progressing so fast presently - one day it may be possible to treat all cancers surrounded by one hit - who knows for sure.
mpossible, Source(s): nurse
If you had chemo drugs in your body every light of day, your blood count could go down so low that you will die.
If you want a chemo drug to kill only the cancer cell, than you would have to change the way your cell gow...impossible.
Julie, every cell has that protein. It's normally still in healthy, normal cell. NF-kappa-B is a protein found in both normal and tumor cells. It is typically immobile because it is bound by another protein called inhibitor of kappa B (I-kappa B)-alpha. When this inhibitor protein is broken down by proteasomes, the NF-kappa-B is now active and can travel to the nucleus where on earth DNA lives. Once there, the active NF-kappa-B starts a chain of events that promote tumor growth and spread.
My first sentence be directed at Jamand and the assertion that everyone has cancer cells in them.
e is a certain protein that cancer cell carry that no other cells in our body fetch. They are trying to create something to target that protein.
Trust me, it does work. I was given less than a month to live with 0% within 2000.
What they did it take T-cells that were collected from me before I ever have any chemo put in my body. They created a vaccine and used it along with interleuken 2. It was designed to attack and waste that protein which the cancer cells carry.
I was the first soul to try this and it did work. It was at the National Cancer Institute in Bethesda, MD, which is where most of the drugs are created.
Although these spanking new medications are more targeted they still have serious side effects and have the potential to injure healthy cells. Old chemotherapeutics attacked any rapidly dividing cell. This leads to side effects like reducing the immune system, anemia, nausea, diarrhea, hair loss, mouth sores, etc. The bin liner of the GI tract, blood cells, hair follicles are all fast dividing cells.
e new medications try to target features that are predominantly found surrounded by in cancer cells. Over expression of certain receptors, the obligation to stimulate new blood vessel growth are some examples. These features though can be found in healthy cell. Certain treatments for lung and colon cancer can cause painful skin rashes since skin cell contain the same receptors the medication. Blocking the growth of new blood vessels can increase the risk of both bleeding and clotting.
Further more treatments are specific for trustworthy cancers. Even within the same cancer, some targeted therapy are worthless if specific mutations are present in the cancer cells.
Secondly, both chemo and radiotherapy work on cancer because they are whats known as cytotoxic - toxic to cells. As well as slaughter cancer cells - this toxicity also makes them carcinogenic in themselves - which is why neither treatment is used for any other complaint except cancer - where the risk/benefit ratio is the right way around. Thus to give chemo to someone lacking cancer - you would be more likely to cause a cancer than 'cure' or prevent one in such untimely stages that you seem to be talking about.
Finally cancer cell rarely start 'in the blood' unless you have leukaemia (and even that starts within the bone marrow where blood cells are made) - chemo agents are administered intravenously as that's the best way to receive the drugs to the site they are needed (and unfortunately also to places they are not - hence all the side effects mentioned in a previous answer). With this contained by mind, I can't see how you can get a cell killing drug in to any factor of the body that won't at least affect the blood cells that have to convey the drug around.
Related Questions: