Why is bone marrow transplantation merely available for a smal number of clients beside sickle cell disease?
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Answers: The above is pretty much right. I wanted to add that in integration to the complications, the actual transplant it self is a VERY traumatic treatment. Many patients who go through it die before they know if it worked. Its also incredably expensive. Beyond the costs involved with the actual treatment and seizure, the patient will be out of work for a min of a year.
bone marrow transplant accounts for an overwhelming majority of the 70 some diseases adult stem cells can treat. But something close to 2/3 of the patients who need it dont have a matched donor, and a matched donor is INCREDABLY important.
When you nick the complications, risks, costs, min 1 year recovery time frame and lack of donors.... For many nation with some of these diseases, the transplant just isnt feasible or worth the risk if their disease can be manage by other means.
There are serious complications involved with receiving donor bone marrow. Matching a donor to a long-suffering is very complex. One serious complication is called graft versus host disease (GVHD) while it is rare if you develop this complication in that is a 90% death rate. Sickle cell crisis may be necessary to treat with RBC transfusion. Recieving mulitple transfusions motivation alloantibiodies to be produced by the immune system and this would further complicate a bone marrow trasplantation. Source(s): book: concepts of immunohematology 2nd ed.
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Answers: The above is pretty much right. I wanted to add that in integration to the complications, the actual transplant it self is a VERY traumatic treatment. Many patients who go through it die before they know if it worked. Its also incredably expensive. Beyond the costs involved with the actual treatment and seizure, the patient will be out of work for a min of a year.
bone marrow transplant accounts for an overwhelming majority of the 70 some diseases adult stem cells can treat. But something close to 2/3 of the patients who need it dont have a matched donor, and a matched donor is INCREDABLY important.
When you nick the complications, risks, costs, min 1 year recovery time frame and lack of donors.... For many nation with some of these diseases, the transplant just isnt feasible or worth the risk if their disease can be manage by other means.
There are serious complications involved with receiving donor bone marrow. Matching a donor to a long-suffering is very complex. One serious complication is called graft versus host disease (GVHD) while it is rare if you develop this complication in that is a 90% death rate. Sickle cell crisis may be necessary to treat with RBC transfusion. Recieving mulitple transfusions motivation alloantibiodies to be produced by the immune system and this would further complicate a bone marrow trasplantation. Source(s): book: concepts of immunohematology 2nd ed.
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