What is the life expectancy after a double lung transplant?

I'm 17, male, and I have CF. I was diagnosed at 6 years old, and my disease is considered relatively 'mild'. I don't really have the pancreatic or digestive problems. I have bad lungs and that's pretty much it. But they've been progressively worse and my doctors are putting me on a waiting list for a double lung transplant, in 1-2 years. I cough up a lot of blood and I always have a lung infection. It's been getting way harder for me to breathe so I've dropped out of soccer and hockey. I'm just wondering, will this lung transplant improve my life expectancy, or shorten it? Will I have to keep getting lung transplants every 5 years? Will it actually make my life better? Thanks.
Answers:     A few websites:
ref="http://www.columbiasurgery.org/pat/lungtx/guide_surgery.html" rel="nofollow">http://www.columbiasurgery.org/pat/lungt…
uble-lung transplant, also known as a bilateral transplant, can be executed either sequentially, en bloc, or simultaneously. Sequential is more common than en bloc.[2] This is effectively like having two separate single-lung transplants done. A less common alternative is the transplantation of both lungs en bloc or simultaneously.

The transplantation process starts after the donor lungs are inspected and the decision to transplant has been made. An incision is then made from under the patient's armpit, around to the sternum, and then back towards the other armpit, this is known as a clamshell incision. In the case of a sequential transplant the recipients lung with the poorest lung functions is collapsed, the blood vessels tied off, and cut at the corresponding bronchi. The new lung is then placed and the blood vessels reattached. To make sure the lung is satisfactory before transplanting the other a bronchoscopy is performed. When the surgeons are satisfied with the performance of the new lung, surgery on the second lung will proceed. In 10% to 20% of double-lung transplants the patient is hooked up to a heart-lung machine which pumps blood for the body and supplies fresh oxygen.[1]

...I'm so sorry.
That made me sad.

website says the average is 8 years, but some are still alive after 15 years.
Some patients need multiple lung transplants.
Patients should be up and walking around within 2 days after surgery.
Patients with CF will stay have it, but it won't directly effect the lungs.
ref="http://en.wikipedia.org/wiki/Lung_transplantation" rel="nofollow">http://en.wikipedia.org/wiki/Lung_transp…
you could read through that...it has some information.
I cant really say i know what your going through but I can say this I have a cousing that has CF and it is extremely bad. He is 6 years old and has to have a ling transplant as well as a liver transplant if he does not he will not survive his next couple of years. From what the doctor has said yes it will increase your survival rate if the lungs are compatable with your body and if your body does no reject them. If you do not I am afraid to say that you may only have what the doctor has told you to live ( i cant make that judgement im no doctor) Or you may surprise everyone and live longer. But it is neccessary to live with so it would be great to get. With every procedure there is chances that something will go wrong ( not trying to scare you) and there is a chance you may or may not come out of it. I wish you extremely great amount of luck and hope all goes well you are in my prayers
Nol! Why the heck did you say that!? You are going to have me worried now! I found as much info as I could!! You have made me very sad! You broke my heart with this question!!
Lung transplant patients who receive two lungs are twice as likely to live more than 10 years than patients who receive one lung are, Johns Hopkins transplant surgeons say.

“Our results suggest that double-lung transplants have a long-term advantage, and surgeons should consider bilateral lung transplants whenever possible,” senior investigator Dr. Ashish Shah, an associate professor at the Johns Hopkins University School of Medicine and its Heart Institute, said in a Hopkins news release.
finding from their analysis of patient records for all single- and double-lung transplants performed in Canada and the United States from 1987 to 1997 is potentially controversial. That’s because there’s a shortage of lung donors, and promoting more double-lung transplants could almost halve the number of potential lung recipients.

“Not all lung recipients necessarily need a bilateral transplant. Many people with chronic obstructive pulmonary disease, including emphysema and different kinds of pulmonary fibrosis, can survive with just one lung being replaced, while other lung diseases, such as cystic fibrosis, usually require transplantation of both lungs. But double-lung transplants clearly perform better over time,” Shah said.

Shah and colleagues also found that a perfect or near perfect match between the donor’s and recipient’s immune-activating protein antigens and having a college education increases the chances for long-term survival by 38 percent and 40 percent, respectively.

Currently, about 17 percent of all lung transplant patients survive 10 years or longer. That’s “pretty good, but not good enough,” Shah said.
study was presented Wednesday at the annual meeting of the International Society for Heart & Lung Transplantation, in Paris.

Lung transplantation increases the survival of patients with cystic fibrosis by almost 4.5 years on average, according to a study presented at the American Thoracic Society International Conference in Orlando on May 24.

"Initially the risks from lung transplantation for cystic fibrosis patients are quite high, but the risk drops over time, and it becomes worth the risk in the long run," said study co-author Roger D. Yusen, MD, MPH, Assistant Professor of Medicine in the Divisions of Pulmonary and Critical Care Medicine and General Medical Sciences at Washington University School of Medicine in St. Louis.
ic fibrosis (CF) is the most common lethal genetic disease in Caucasians, but it affects all races and ethnic groups. The disease affects about 30,000 people in the United States. Approximately 1,000 new cases are diagnosed every year. People with CF live an average of 33 years. They develop severe lung disease, with a combination of airway obstruction, infection, and inflammation that accounts for the majority of deaths from the dis�ease.

CF patients who receive lung transplants to treat their disease must have a double lung transplant in order for the surgery to be effective, said Dr. Yusen. Lung transplants are not common--approximately 1,000 are performed each year in the United States, and only 150 of them, or 15%, are performed on CF patients. "In the United States, lungs are distributed to patients on the waiting list based primarily on their waiting time, whereas the system for patients waiting for heart or liver transplant depends highly on medical urgency," explained Dr. Yusen.

Dr. Yusen and colleagues studied all patients with CF who were on the waiting list for lung transplantation at Washington University School of Medicine and Barnes-Jewish Hospital in St. Louis since the program began in 1988. The study included 247 patients, who were followed through 2002. Most were Caucasian, reflecting the CF population as a whole, and the average age at the time of placement on the waiting list was 28. All the patients had severely impaired lung function and severe symptoms when they were placed on the waiting list.

Of the 247 patients in the study, after one year, 84% of patients were alive while waiting for a transplant, and an equal percentage were alive after having a transplant. After two years, 67% of those waiting for a transplant were alive, compared with 76% who had a transplant. After five years, 55% of transplant patients were alive.
gh transplantation had a significant early death risk compared with continued waiting, the risks significantly decreased over time. Within 15 months, the survival benefit from transplantation became apparent. Based on an average survival of 5.7 years after transplant, the researchers determined that lung transplantation improved the life expectancy of patients with CF by almost 4.5 years.

"Next, we hope to see if transplanted patients are not only living longer, but enjoying a better quality of life than those who remain on the waiting list," Dr. Yusen said.

We followed all adult patients consecutively listed for first, lung-only transplantation between 1990 and 1996 (n = 1,208) for at least 2 years, with an additional 2-year follow-up after transplantation (n = 744). We used the competing risk method, the Kaplan-Meier method, and a time-dependent non-proportional hazards model to analyze waiting-list outcome and global mortality after listing, post-transplant survival, and transplant effect, respectively. Each analysis was stratified for type of end-stage lung disease.


Lung transplantation conferred transplant benefit in a Western European cohort of adults, in particular for patients with pulmonary fibrosis and cystic fibrosis, but also for patients with emphysema. The global survival rate, reflecting the real life expectancy for a newly listed transplant candidate, is poor for patients with pulmonary fibrosis and pulmonary hypertension. Allocation algorithms that lessen the impact of waiting time and take into account the type of end-stage lung disease should be developed.

ng transplant is a surgical procedure that is performed on patients who are suffering from end-stage lung disease
, an irreversible condition that can result from a number of disorders. A lung transplant is performed to replace a lung or pair of lungs that is unable to perform adequate gas exchange. This may be the result of end-stage lung diseases, such as severe cases of emphysema, pulmonary fibrosis, cystic fibrosis, and pulmonary hypertension.

To become a candidate for lung transplant, a patient will meet with a pulmonologist to discuss the advantages and disadvantages of the procedure. Factors that must be weighed include quality of life and life expectancy. Because post-operative care requires a great deal of support, friends and family should be involved with the decision process. After the patient undergoes several tests and exams, his or her case will be presented to a committee of specialists for review. Depending on the patient’s condition, the committee will decide whether transplantation is a suitable option. If the committee decides not to accept the patient as a candidate, further tests or an alternate therapy may be recommended. Once on the list, the candidate will be placed on the United Network for Organ Sharing. The method of selection will be explained in detail to the patient. While on the waiting list, patients and the transplant team will be in close contact.
ngle lung transplant is most clearly indicated for patients with restrictive lung disease. Advantages are the relative simplicity of the surgical procedure, which avoids systemic anticoagulation and cardiopulmonary bypass; the greater range acceptable for donor/recipient size match; and the optimal use of organs with the heart (and the contralateral lung) available for other recipients. Disadvantages include the possibility of ventilation/perfusion mismatch between the native and transplant lungs and poor healing of the bronchial anastomosis. Wrapping of the bronchial anastomosis with omentum has ameliorated but not eliminated the latter problem. A double lung transplant removes all diseased lung tissue and theoretically is applicable in all patients who have no irreversible cardiac abnormality. However, division of the donor bronchial arteries and bronchocoronary collaterals makes tracheal healing problematic.

Advantages of double lung and heart-lung transplantation are the removal of all potentially diseased tissue from the thorax and, for heart-lung transplantation, a more dependable healing of the tracheal anastomosis because coronary-bronchial collaterals are present within the heart-lung block. Disadvantages are the more extensive na

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